The 2-Minute Rule for modafinil dosage

The 2-Minute Rule for modafinil dosage

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In animal scientific tests, the median lethal dose (LD50) of modafinil differs among species and depends on the route of administration. In mice and rats, the LD50 is approximately 1250 mg/kg if administered by means of an injection, nevertheless the oral LD50 for rats is 3400 mg/kg.

acetazolamide will boost the stage or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.

apalutamide will minimize the extent or impact of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Prevent or Use Alternate Drug. Coadministration of apalutamide, a solid CYP2C19 inducer, with medications which might be CYP2C19 substrates may result in reduce exposure to those prescription drugs.

Moreover, if taking modafinil on a daily basis, the concentrations in your bloodstream can start to Make up after a while.

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Doses up to 400 mg/working day, specified as only one dose, are actually nicely tolerated, but there's no dependable proof this dose confers added gain outside of that on the 200 mg/day dose

drospirenone will improve the amount or outcome of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.

nelfinavir will raise the stage or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

tazemetostat will minimize the level or impact of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

Major skin reactions can occur with this particular medication. Quit working with this drugs and Verify with all your health practitioner immediately When you've got blistering, peeling, or loosening of the skin; purple pores and skin lesions; severe acne or pores and skin rash; sores or ulcers on the skin; or fever or chills if you are using this medication. This medication may perhaps induce you to obtain a serious form of allergic response termed anaphylaxis. Anaphylaxis could be lifetime-threatening and calls for fast professional medical attention. Quit taking this medicine and contact your medical professional without delay When you've got a pores and skin rash; itching; hives; hoarseness; difficulties respiration; difficulties swallowing; or any swelling of one's hands, face, or mouth while you are applying this drugs. This medication may possibly trigger click here major allergic reactions impacting numerous body organs (e.g., coronary heart, liver, or blood cells). Quit utilizing this drugs and Test using your medical professional straight away For those who have the following indications: chest discomfort or soreness, fever and chills, darkish urine, headache, rash, stomach suffering, abnormal tiredness, unusual bleeding or bruising, or yellow eyes or pores and skin. If you think modafinil is not Operating thoroughly Once you have taken it for a several weeks, never improve the dose.

Allergies Tell your physician if you have at any time had any uncommon or allergic reaction to this drugs or almost every other medicines.

This medication is accessible only with the health care provider's prescription. This solution is offered in the following dosage types:

It isn't identified whether modafinil passes into breast milk or if it could harm a nursing toddler. Explain to your health care provider If you're breast-feeding a baby.